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KMID : 0388420010110010141
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Konkuk Journal of Medical Sciences
2001 Volume.11 No. 1 p.141 ~ p.148
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6 Cases of Dimecron Intoxication
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Ryu Ha-Kun
Park Bong-An
Ryu Ju-Sung
Yu Jae-Deung
Kim Jung-Su
Kim Chi-Hun
Song Jong-Oh
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Abstract
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The authors experienced 6 cases of Dimecron intoxication, an organophosphate, that required mechanical ventilator treatment. Among 6 cases, 4 cases were intoxication due to suicidal attempt and 2 cases were due to accidental exposure. Among 4 cases of intoxication due to suicidal attempt, only one patient recovered even after aggressive treatments using gastric lavage, mechanical ventilation, atropine and PAM(pralidoxime). Two cases of intoxications due to accidental exposure, 1 case needed mechanical ventilation. Both cases were recovered without any sequele, however, Organophosphate, especially Dimecron, showed high rates of respiratory muscle paralysis and mechanical ventilator support. The mortality rate of organophosphate agents can be decreased by education, wearing protectors, and aggressive mechanical ventilator treatment when respiratory failure develops.
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KEYWORD
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intoxication, organophosphate, dimecron, mechanical ventilation
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